Epithelial-mesenchymal transition (EMT) is a biological process in which epithelial cells lose their cell polarity and cell-cell adhesion properties, and gain the characteristics of mesenchymal cells. This transition is essential for various physiological processes such as embryogenesis and wound healing, but aberrant EMT has been implicated in cancer progression and metastasis. During EMT, epithelial cells undergo molecular changes that allow them to become more migratory and invasive, enabling them to leave their original location and invade surrounding tissues. This process is regulated by various signaling pathways and transcription factors, and is associated with changes in cell morphology and gene expression. Research in the field of EMT aims to understand the molecular mechanisms underlying this process, its role in normal development and disease progression, as well as its potential therapeutic implications. Studying EMT may provide insights into the mechanisms of cancer metastasis and help identify potential targets for therapy.